Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12955427 | 1.00 | HRH3 (0.32) | HRH3AOC3NR1H4CYP11B1CYP11B2 | |
| SCHEMBL14435633 | 0.90 | HRH3 (0.33) | HRH3AOC3NR1H4CYP11B1CYP11B2 | |
| SCHEMBL14434682 | 0.89 | HRH3 (0.32) | HRH3AOC3NR1H4CYP11B1CYP11B2 | |
| SCHEMBL12955556 | 0.86 | MCHR1 (0.36) | AOC3NR1H4CYP11B1CYP11B2 | |
| SCHEMBL14434678 | 0.86 | MCHR1 (0.39) | AOC3NR1H4 | |
| SCHEMBL13903196 | 0.85 | HRH3 (0.39) | HRH3AOC3NR1H4 | |
| SCHEMBL4122423 | 0.85 | HRH3 (0.39) | HRH3AOC3NR1H4 | |
| SCHEMBL12955579 | 0.77 | MCHR1 (0.39) | AOC3 | |
| SCHEMBL13903175 | 0.76 | HRH3 (0.43) | HRH3AOC3NR1H4 | |
| SCHEMBL13903194 | 0.74 | HRH3 (0.40) | HRH3AOC3NR1H4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093366-A1 | NOVEL AMINOALCOHOL-SUBSTITUTED ARYLDIHYDROISOQUINOLINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2007-08-23 | — | — | WO | disclosed |