SCHEMBL14435952

SCHEMBL14435952

CC(=O)OC1C(CO)OC(O[C@]2(CO)OC(CO)[C@H](OC(C)=O)[C@H]2OC(C)=O)C(OC(C)=O)C1OC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.39
THRB P10828 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA2 P00918 5/20 0.35
CA1 P00915 4/20 0.35
CA4 P22748 4/20 0.35
CA5A P35218 4/20 0.35
CA5B Q9Y2D0 4/20 0.35
CA12 O43570 3/20 0.35
CA7 P43166 3/20 0.35
EPHX2 P34913 3/20 0.35
CDK1 P06493 1/20 0.34
CCNB1 P14635 1/20 0.34
LDHA P00338 1/20 0.34
TSHR P16473 1/20 0.31
NR3C1 P04150 1/20 0.31
FYN P06241 1/20 0.31
ADRA2A P08913 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADRA2B P18089 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13297616 1.00 CYP2D6 (0.39) CYP2D6THRBHSD17B10CA2CA1
SCHEMBL13777015 1.00 CYP2D6 (0.39) CYP2D6THRBHSD17B10CA2CA1
SCHEMBL2888522 1.00 CYP2D6 (0.39) CYP2D6THRBHSD17B10CA2CA1
SCHEMBL3418339 0.90 CDK1 (0.40) CYP2D6THRBHSD17B10CA2EPHX2
SCHEMBL4581259 0.89 CYP2D6 (0.42) CYP2D6THRBHSD17B10CA2CA1
SCHEMBL745908 0.86 EPHX2 (0.33) EPHX2CDK1CCNB1LDHA
SCHEMBL14435948 0.85 CYP2D6 (0.41) CYP2D6THRBHSD17B10CA2CA1
SCHEMBL13297613 0.85 CYP2D6 (0.41) CYP2D6THRBHSD17B10CA2CA1
SCHEMBL8038328 0.84 CYP2D6 (0.47) CYP2D6THRBHSD17B10CA2CA1
SCHEMBL13777010 0.83 CYP2D6 (0.41) CYP2D6EPHX2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007096726-A2 PROCESS FOR THE PREPARATION OF A GLUCOSE DERIVATIVE EMCURE PHARMACEUTICALS LIMITED (IN) 2007-08-30 WO disclosed