Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ANPEP | P15144 | 2/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274004 | 1.00 | KDM4E (0.56) | KDM4EANPEPERAP2HTTSMN1; SMN2 | |
| SCHEMBL19215547 | 0.93 | — | — | |
| SCHEMBL22229848 | 0.88 | — | — | |
| SCHEMBL22361086 | 0.88 | — | — | |
| SCHEMBL3254068 | 0.88 | — | — | |
| SCHEMBL10462730 | 0.86 | KDM4E (0.47) | KDM4EANPEPERAP2HTTSMN1; SMN2 | |
| SCHEMBL1043149 | 0.83 | KDM4E (0.62) | KDM4EANPEPERAP2HTTSMN1; SMN2 | |
| SCHEMBL7775092 | 0.83 | KDM4E (0.62) | KDM4EANPEPERAP2HTTSMN1; SMN2 | |
| SCHEMBL7775213 | 0.83 | KDM4E (0.62) | KDM4EANPEPERAP2HTTSMN1; SMN2 | |
| SCHEMBL28834983 | 0.83 | KDM4E (0.52) | KDM4EANPEPERAP2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475673-A1 | CYCLOBUTAN-1,1 -DICARBOXYLATO COMPLEXES OF PLATINUM WITH N6-BENZYLADENINE DERIVATIVES, METHOD OF THEIR PREPARATION AND APPLICATION OF THESE COMPLEXES AS DRUGS IN ANTITUMOUR THERAPY | Univerzita Palackeho (CZ) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011029415-A1 | CYCLOBUTAN-1,1 -DICARBOXYLATO COMPLEXES OF PLATINUM WITH N6-BENZYLADENINE DERIVATIVES, METHOD OF THEIR PREPARATION AND APPLICATION OF THESE COMPLEXES AS DRUGS IN ANTITUMOUR THERAPY | UNIVERZITA PALACKEHO (CZ) | 2011-03-17 | — | — | WO | disclosed |