Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 15/20 | 0.64 |
| ▸ | MEN1 | O00255 | 14/20 | 0.64 |
| ▸ | POLB | P06746 | 7/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5503552 | 0.90 | KMT2A (0.66) | KMT2AMEN1POLBL3MBTL1NCOA3 | |
| SCHEMBL14437269 | 0.89 | KMT2A (0.58) | KMT2AMEN1POLBL3MBTL1NCOA3 | |
| SCHEMBL14437290 | 0.87 | KMT2A (0.60) | KMT2AMEN1POLBL3MBTL1NCOA3 | |
| SCHEMBL14437284 | 0.86 | MEN1 (0.47) | KMT2AMEN1POLBL3MBTL1NCOA3 | |
| SCHEMBL14437307 | 0.85 | KMT2A (0.49) | KMT2AMEN1POLBL3MBTL1NCOA3 | |
| SCHEMBL14437304 | 0.83 | KMT2A (0.52) | KMT2AMEN1POLBL3MBTL1NCOA3 | |
| SCHEMBL14437303 | 0.82 | KMT2A (0.49) | KMT2AMEN1POLBL3MBTL1NCOA3 | |
| SCHEMBL5499618 | 0.82 | KMT2A (0.44) | KMT2AMEN1POLBL3MBTL1NCOA3 | |
| SCHEMBL5502571 | 0.81 | KMT2A (0.47) | KMT2AMEN1POLBL3MBTL1NCOA3 | |
| SCHEMBL14437297 | 0.80 | KMT2A (0.51) | KMT2AMEN1POLBL3MBTL1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253285-B2 | Thiazolinone 4-monosubstituted quinolines | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253285-B2 | Thiazolinone 4-monosubstituted quinolines | HOFFMANN-LA ROCHE INC. (US) | 2007-08-07 | — | — | US | disclosed |