SCHEMBL14438579

SCHEMBL14438579

CC(C)[Si]1(C(C)C)OC[C@H]2CN(C(=O)OCC3c4ccccc4-c4ccccc43)C[C@@H]2O[Si](C(C)C)(C(C)C)O1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FABP5 Q01469 3/20 0.34
▸ F10 P00742 2/20 0.34
▸ FABP7 O15540 2/20 0.33
▸ CASP3 P42574 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ PIN1 Q13526 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ MDM4 O15151 1/20 0.32
▸ TP53 P04637 1/20 0.32
▸ EPHX2 P34913 1/20 0.32
▸ PARP1 P09874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14438578 1.00 FABP5 (0.34) FABP5F10FABP7CASP3KMT2A
SCHEMBL5485683 0.74 KMT2A (0.46) FABP5F10FABP7KMT2APOLB
SCHEMBL119453 0.68 FABP5 (0.52) FABP5F10FABP7CASP3KMT2A
SCHEMBL25807850 0.68 KMT2A (0.44) FABP5F10FABP7CASP3KMT2A
SCHEMBL30491856 0.68 KMT2A (0.44) FABP5F10FABP7CASP3KMT2A
SCHEMBL4709998 0.68 FABP5 (0.49) FABP5F10FABP7CASP3KMT2A
SCHEMBL22397770 0.68 POLB (0.52) FABP5FABP7KMT2APOLBEPHX2
SCHEMBL13327274 0.68 POLB (0.52) FABP5FABP7KMT2APOLBEPHX2
SCHEMBL6855032 0.67 KMT2A (0.46) FABP5F10FABP7CASP3KMT2A
SCHEMBL7926629 0.67 KMT2A (0.46) FABP5F10FABP7CASP3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070179100-A1 Protected monomers ALNYLAM PHARMACEUTICALS, INC. 2007-08-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070179100-A1 Protected monomers PCNA, POLN, PARP1 FABP5 2373/4885F10 3554/4885FABP7 3945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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