Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 9/20 | 1.00 |
| ▸ | IDO1 | P14902 | 4/20 | 0.64 |
| ▸ | NQO1 | P15559 | 3/20 | 0.64 |
| ▸ | POR | P16435 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | GMNN | O75496 | 1/20 | 0.64 |
| ▸ | TDP2 | O95551 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439374 | 0.83 | MALT1 (0.71) | MALT1IDO1NQO1PORSMN1; SMN2 | |
| SCHEMBL14439372 | 0.81 | MALT1 (0.90) | MALT1IDO1NQO1PORSMN1; SMN2 | |
| SCHEMBL14456608 | 0.81 | MALT1 (0.71) | MALT1IDO1NQO1PORSMN1; SMN2 | |
| Lapachone SCHEMBL107042 | 0.79 | MALT1 (1.00) | MALT1IDO1NQO1PORSMN1; SMN2 | |
| SCHEMBL5940394 | 0.79 | MALT1 (0.74) | MALT1IDO1NQO1PORSMN1; SMN2 | |
| SCHEMBL13611278 | 0.78 | MALT1 (0.64) | MALT1IDO1NQO1PORSMN1; SMN2 | |
| SCHEMBL5940435 | 0.78 | MALT1 (0.75) | MALT1IDO1NQO1PORSMN1; SMN2 | |
| SCHEMBL12473165 | 0.76 | MALT1 (0.61) | MALT1IDO1NQO1PORSMN1; SMN2 | |
| SCHEMBL5940140 | 0.76 | MALT1 (0.71) | MALT1IDO1NQO1PORSMN1; SMN2 | |
| SCHEMBL14439327 | 0.73 | MALT1 (0.57) | MALT1IDO1NQO1PORSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |
| US-7253207-B2 | Quinones as disease therapies | CELLGATE, INC. (US) | 2007-08-07 | — | — | US | disclosed |