Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12094860 | 1.00 | HDAC6 (0.59) | HDAC6HDAC1HDAC8 | |
| SCHEMBL1443939 | 1.00 | HDAC6 (0.59) | HDAC6HDAC1HDAC8 | |
| SCHEMBL12094862 | 0.91 | HDAC1 (0.54) | HDAC6HDAC1HDAC8 | |
| SCHEMBL1439957 | 0.91 | HDAC1 (0.54) | HDAC6HDAC1HDAC8 | |
| SCHEMBL12094863 | 0.89 | HDAC1 (0.52) | HDAC6HDAC1HDAC8 | |
| SCHEMBL1439958 | 0.89 | HDAC1 (0.52) | HDAC6HDAC1HDAC8 | |
| SCHEMBL6864353 | 0.88 | HDAC1 (0.51) | HDAC6HDAC1HDAC8 | |
| SCHEMBL1441260 | 0.87 | HDAC6 (0.50) | HDAC6HDAC1HDAC8 | |
| SCHEMBL1441263 | 0.87 | HDAC6 (0.50) | HDAC6HDAC1HDAC8 | |
| SCHEMBL6863129 | 0.87 | HDAC1 (0.55) | HDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | claimed |
| WO-2007054776-A9 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-03-03 | — | — | WO | claimed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | claimed |
| WO-2007054776-A2 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-05-18 | — | — | WO | claimed |
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | HDAC1, HDAC5, HDAC11 | HDAC6 9/4885HDAC1 1/4885HDAC8 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.