⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443410 | 1.00 | — | — | |
| SCHEMBL1443426 | 1.00 | — | — | |
| SCHEMBL1443086 | 1.00 | — | — | |
| SCHEMBL1443395 | 1.00 | — | — | |
| SCHEMBL1443621 | 1.00 | — | — | |
| SCHEMBL1444502 | 1.00 | — | — | |
| SCHEMBL1444400 | 1.00 | — | — | |
| SCHEMBL1443983 | 1.00 | — | — | |
| SCHEMBL1443384 | 1.00 | — | — | |
| SCHEMBL1443709 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090370-A1 | PHARMACOLOGICALLY ACTIVE AGENTS CONTAINING ESTERIFIED PHOSPHONATES AND METHODS FOR USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-09-29 | — | — | WO | claimed |
| US-20050192246-A1 | Pharmacologically active agents containing esterified phosphonates and methods for use thereof | US ARMY, SECRETARY OF THE ARMY | 2005-09-01 | — | — | US | claimed |
| CN-101189249-B | Phosphono-pent-2-en-1-yl nucleosides and analogs | UNIV CALIFORNIA | 2013-04-17 | — | — | CN | disclosed |
| US-20130018018-A1 | NOVEL NUCLEOSIDE PHOSPHONATES AND ANALOGS | Epiphany Biosciences ,Inc. (US) | 2013-01-17 | — | — | US | disclosed |
| CN-102781462-A | Novel nucleoside phosphonates and analogs | EPIPHANY BIOSCIENCES INC | 2012-11-14 | — | — | CN | disclosed |
| US-8222257-B2 | Phosphono-pent-2-en-1-yl nucleosides and analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-17 | — | — | US | disclosed |
| EP-2470194-A1 | NOVEL NUCLEOSIDE PHOSPHONATES AND ANALOGS | Epiphany Biosciences Inc. (US) | 2012-07-04 | — | — | EP | disclosed |
| US-8193167-B2 | Pharmacologically active agents containing esterified phosphonates and methods for use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-05 | — | — | US | disclosed |
| EP-1866319-B1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | UNIV CALIFORNIA (US) | 2011-11-23 | — | — | EP | disclosed |
| WO-2011031567-A1 | NOVEL NUCLEOSIDE PHOSPHONATES AND ANALOGS | EPIPHANY BIOSCIENCES, INC. (US) | 2011-03-17 | — | — | WO | disclosed |
| US-20100273742-A1 | Pharmacologically Active Agents Containing Esterified Phosphonates and Methods for Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-10-28 | — | — | US | disclosed |
| US-20090156545-A1 | Substituted Phosphate Esters of Nucleoside Phosphonates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-06-18 | — | — | US | disclosed |
| CN-101189249-A | Phosphono-pent-2-en-1-yl nucleosides and analogs | UNIVERISITY OF CALIFORNIA (US) | 2008-05-28 | — | — | CN | disclosed |
| EP-1866319-A1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006137953-A1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | THE REGENTS OF THE UNIVERISITY OF CALIFORNIA (US) | 2006-12-28 | — | — | WO | disclosed |
| WO-2006130217-A2 | SUBSTITUTED PHOSPHATE ESTERS OF NUCLEOSIDE PHOSPHONATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006076015-A2 | 1-[2-(PHOSPHONOMETHOXY)ETHYL]-CYTOSINE AND ANALOGS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | disclosed |
| WO-2005090370-A1 | PHARMACOLOGICALLY ACTIVE AGENTS CONTAINING ESTERIFIED PHOSPHONATES AND METHODS FOR USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005087788-A2 | METHODS FOR PREPARATION OF NUCLEOSIDE PHOSPHONATE ESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050192246-A1 | Pharmacologically active agents containing esterified phosphonates and methods for use thereof | US ARMY, SECRETARY OF THE ARMY | 2005-09-01 | — | — | US | disclosed |