Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645405 | 1.00 | AR (0.43) | ARCYP2C19RORC | |
| SCHEMBL14440692 | 0.82 | AR (0.46) | ARCYP2C19 | |
| SCHEMBL5640722 | 0.82 | AR (0.46) | ARCYP2C19 | |
| SCHEMBL14440675 | 0.82 | AR (0.45) | AR | |
| SCHEMBL5640728 | 0.82 | AR (0.45) | AR | |
| SCHEMBL27477899 | 0.71 | AR (0.44) | AR | |
| SCHEMBL14440681 | 0.67 | AR (0.49) | ARCYP2C19 | |
| SCHEMBL5640316 | 0.67 | AR (0.49) | ARCYP2C19 | |
| SCHEMBL3572906 | 0.67 | AR (0.45) | ARCYP2C19 | |
| SCHEMBL5640909 | 0.67 | AR (0.47) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256208-B2 | Monocyclic N-Aryl hydantoin modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-14 | — | — | US | disclosed |
| US-7256208-B2 | Monocyclic N-Aryl hydantoin modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-14 | — | — | US | disclosed |