Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.58 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.47 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.47 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.47 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.47 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.47 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.47 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429901 | 0.94 | S1PR3 (0.64) | S1PR3SOAT1L3MBTL1GAATDP1 | |
| SCHEMBL14429926 | 0.88 | PSMB11 (0.52) | S1PR3SOAT2SOAT1CNR1L3MBTL1 | |
| SCHEMBL9502168 | 0.87 | GAA (0.64) | SOAT2SOAT1CNR1L3MBTL1GAA | |
| SCHEMBL9502155 | 0.87 | GAA (0.64) | SOAT2SOAT1CNR1L3MBTL1GAA | |
| SCHEMBL4386284 | 0.87 | S1PR3 (0.74) | S1PR3SOAT2SOAT1CNR1L3MBTL1 | |
| SCHEMBL14441039 | 0.85 | S1PR3 (0.56) | S1PR3SOAT1L3MBTL1GAATDP1 | |
| SCHEMBL14440895 | 0.85 | S1PR3 (0.56) | S1PR3SOAT1L3MBTL1GAATDP1 | |
| SCHEMBL14441294 | 0.84 | S1PR3 (0.49) | S1PR3L3MBTL1GAATDP1POLB | |
| SCHEMBL14441001 | 0.83 | S1PR3 (0.54) | S1PR3SOAT1L3MBTL1GAATDP1 | |
| SCHEMBL5461336 | 0.82 | S1PR3 (0.53) | S1PR3L3MBTL1GAATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185176-A1 | Heparanase inhibitors and uses thereof | INSIGHT BIOHARMACEUTICALS LTD. (IL) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185176-A1 | Heparanase inhibitors and uses thereof | HPSE, ENGASE, HEXA | S1PR3 1318/4885SOAT2 4339/4885SOAT1 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.