Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLN | Q9BYT8 | 3/20 | 0.64 |
| ▸ | PARP1 | P09874 | 7/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359466 | 0.83 | PARP1 (0.66) | PARP1LMNAMAPTBAZ2B | |
| SCHEMBL8359720 | 0.81 | PARP1 (0.56) | NLNPARP1LMNAMAPTBAZ2B | |
| SCHEMBL8359478 | 0.81 | PARP1 (0.60) | PARP1LMNAMAPTBAZ2B | |
| SCHEMBL8359708 | 0.81 | PARP1 (0.60) | PARP1LMNAMAPTBAZ2B | |
| SCHEMBL8359603 | 0.78 | PARP1 (0.74) | PARP1LMNAMAPTBAZ2B | |
| SCHEMBL8359594 | 0.77 | PARP1 (0.63) | PARP1CYP3A4LMNAMAPTBAZ2B | |
| SCHEMBL8359606 | 0.75 | PARP1 (0.61) | PARP1CYP3A4LMNAMAPTBAZ2B | |
| SCHEMBL8359607 | 0.75 | PARP1 (0.61) | PARP1LMNAMAPTBAZ2B | |
| SCHEMBL8360522 | 0.75 | HDAC8 (0.57) | PARP1 | |
| SCHEMBL8360529 | 0.74 | PARP1 (0.51) | NLNPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247641-B2 | Compounds, derivatives, compositions, preparation and uses | MGI GP, INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-7247641-B2 | Compounds, derivatives, compositions, preparation and uses | MGI GP, INC. (US) | 2007-07-24 | — | — | US | disclosed |