SCHEMBL14445985

SCHEMBL14445985

Cc1cc(CN(C)Cc2cc(-c3ccc(C(F)(F)F)cc3)nn2C)ccc1OC(C)(C)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 20/20 0.56
PPARG P37231 17/20 0.56
PPARD Q03181 15/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14445956 0.91 PPARA (0.46) PPARAPPARGPPARD
SCHEMBL14445987 0.91 PPARA (0.51) PPARAPPARGPPARD
SCHEMBL14445990 0.88 PPARA (0.53) PPARAPPARGPPARD
SCHEMBL14445998 0.88 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL14446020 0.86 PPARA (0.51) PPARAPPARGPPARD
SCHEMBL14445988 0.84 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL13899454 0.84 PPARA (0.50) PPARAPPARGPPARD
SCHEMBL14445976 0.83 PPARA (0.41) PPARAPPARGPPARD
SCHEMBL5904770 0.81 PPARD (0.62) PPARAPPARGPPARD
SCHEMBL14446013 0.81 PPARA (0.51) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7241793-B2 Phenyloxyalkanonic acid derivatives as hPPAR activators SMITHKLINE BEECHAM CORPORATION (US) 2007-07-10 US disclosed
US-7241793-B2 Phenyloxyalkanonic acid derivatives as hPPAR activators SMITHKLINE BEECHAM CORPORATION (US) 2007-07-10 US disclosed