Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1150757 | 0.77 | TSHR (0.36) | KDM4ELMNAMAPTBLMSMN1; SMN2 | |
| SCHEMBL10012157 | 0.77 | TP53 (0.52) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL1151339 | 0.77 | TSHR (0.36) | KDM4ELMNAMAPTBLMSMN1; SMN2 | |
| SCHEMBL373389 | 0.77 | — | — | |
| SCHEMBL1079175 | 0.77 | — | — | |
| SCHEMBL1170371 | 0.77 | TP53 (0.52) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL1117542 | 0.77 | TSHR (0.36) | KDM4ELMNAMAPTBLMSMN1; SMN2 | |
| SCHEMBL1150689 | 0.77 | TSHR (0.36) | KDM4ELMNAMAPTBLMSMN1; SMN2 | |
| SCHEMBL22227354 | 0.77 | TP53 (0.52) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL1117465 | 0.77 | TSHR (0.36) | KDM4ELMNAMAPTBLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477701-A2 | GENTLE DYEING AND LIGHTENING AGENTS HAVING IMPROVED LIGHTENING POWER | Henkel AG & Co. KGaA (DE) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011032762-A2 | GENTLE DYEING AND LIGHTENING AGENTS HAVING IMPROVED LIGHTENING POWER | HENKEL AG & CO. KGAA (DE) | 2011-03-24 | — | — | WO | disclosed |