⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14311830 | 0.98 | SLC6A2 (0.33) | — | |
| SCHEMBL1444960 | 0.86 | — | — | |
| SCHEMBL782327 | 0.84 | — | — | |
| SCHEMBL17754732 | 0.84 | — | — | |
| SCHEMBL22469853 | 0.84 | SLC6A2 (0.36) | — | |
| Hydrochloric Acid SCHEMBL22469308 | 0.82 | SLC6A2 (0.36) | — | |
| Hydrochloric Acid SCHEMBL1991419 | 0.82 | SLC6A2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL3209364 | 0.82 | SLC6A2 (0.32) | — | |
| SCHEMBL1485534 | 0.78 | — | — | |
| Tert-Butyl Formate SCHEMBL28680027 | 0.78 | TDP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326916-A2 | Quinolone- and naphthyridone-carboxylic acid derivatives, method for their preparation and antibacterial agents and food additives containing them | BAYER AG (DE) | 1989-08-09 | — | — | EP | claimed |
| US-11524966-B1 | Carboxamides as ubiquitin-specific protease inhibitors | VALO HEALTH, INC. (US) | 2022-12-13 | — | — | US | disclosed |
| US-20210323975-A1 | CARBOXAMIDES AS UBIQUITIN-SPECIFIC PROTEASE INHIBITORS | VALO EARLY DISCOVERY, INC. | 2021-10-21 | — | — | US | disclosed |
| US-11059784-B2 | Oxime ether compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-07-13 | — | — | US | disclosed |
| US-20210147361-A1 | OXIME ETHER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-05-20 | — | — | US | disclosed |
| US-20210147361-A1 | OXIME ETHER COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-05-20 | — | — | US | disclosed |
| EP-3507278-B1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-01-27 | — | — | EP | disclosed |
| EP-3507278-B1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-01-27 | — | — | EP | disclosed |
| US-10633354-B2 | Substituted tricyclic heterocyclic compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-04-28 | — | — | US | disclosed |
| US-10633354-B2 | Substituted tricyclic heterocyclic compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-04-28 | — | — | US | disclosed |
| CN-1035945-C | 5-Alkylquinolonecarboxylic acids | BAYER AG (DE) | 1997-09-24 | — | — | CN | disclosed |
| EP-0677522-A1 | 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-5453422-A | Animal growth promoters | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| US-5284842-A | Active against gramnegative bacteria | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| US-5252734-A | Antibacterial 5-alkylquinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-12 | — | — | US | disclosed |
| US-5173484-A | Animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| US-5140033-A | For prevention or treatment of bacterial infections in humans or animals | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-18 | — | — | US | disclosed |
| CN-1046162-A | The 5-Alkylquinolonecarboxacids acids | BAYER AG (DE) | 1990-10-17 | — | — | CN | disclosed |
| EP-0391132-A1 | 5-Alkylquinolinone carboxylic acids | BAYER AG (DE) | 1990-10-10 | — | — | EP | disclosed |
| EP-0326916-A2 | Quinolone- and naphthyridone-carboxylic acid derivatives, method for their preparation and antibacterial agents and food additives containing them | BAYER AG (DE) | 1989-08-09 | — | — | EP | disclosed |