Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 6/20 | 0.73 |
| ▸ | KDR | P35968 | 5/20 | 0.73 |
| ▸ | RET | P07949 | 3/20 | 0.73 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.73 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.73 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.73 |
| ▸ | ABL1 | P00519 | 2/20 | 0.73 |
| ▸ | LTK | P29376 | 2/20 | 0.73 |
| ▸ | FLT3 | P36888 | 2/20 | 0.73 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.73 |
| ▸ | CDK7 | P50613 | 2/20 | 0.73 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.73 |
| ▸ | MST1R | Q04912 | 2/20 | 0.73 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.73 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.73 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.73 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.73 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.73 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.73 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5472578 | 1.00 | NTRK1 (0.73) | NTRK1KDRRETPDGFRBPDGFRA | |
| SCHEMBL5472580 | 1.00 | NTRK1 (0.73) | NTRK1KDRRETPDGFRBPDGFRA | |
| SCHEMBL7780557 | 0.90 | NTRK1 (0.78) | NTRK1KDRRETPDGFRBPDGFRA | |
| SCHEMBL5470627 | 0.88 | NTRK1 (0.73) | NTRK1KDRRETPDGFRBPDGFRA | |
| SCHEMBL5470630 | 0.88 | NTRK1 (0.73) | NTRK1KDRRETPDGFRBPDGFRA | |
| SCHEMBL14448924 | 0.88 | NTRK1 (0.73) | NTRK1KDRRETPDGFRBPDGFRA | |
| SCHEMBL14448917 | 0.85 | LRRK2 (0.73) | NTRK1KDRRETPDGFRBPDGFRA | |
| SCHEMBL5464546 | 0.85 | LRRK2 (0.73) | NTRK1KDRRETPDGFRBPDGFRA | |
| SCHEMBL5377292 | 0.85 | NTRK1 (0.73) | NTRK1KDRRETPDGFRBPDGFRA | |
| SCHEMBL7779513 | 0.85 | NTRK1 (0.73) | NTRK1KDRRETPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167488-A1 | Novel therapeutic use | LEO PHARMA A/S (DK) | 2007-07-19 | — | — | US | disclosed |
| US-20070167488-A1 | Novel therapeutic use | LEO PHARMA A/S (DK) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167488-A1 | Novel therapeutic use | MAG, PMP22, MYT1 | NTRK1 175/4885KDR 4334/4885RET 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.