Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 16/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1730396 | 0.99 | F2R (0.60) | F2RMAPTKDM4ENPC1RAB9A | |
| SCHEMBL14449142 | 0.94 | F2R (0.69) | F2RMAPTKDM4ELMNA | |
| Bromide SCHEMBL1729157 | 0.93 | F2R (0.69) | F2RMAPTKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL1731190 | 0.93 | F2R (0.69) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1729568 | 0.93 | F2R (0.58) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL5487388 | 0.92 | F2R (0.69) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1729420 | 0.92 | F2R (0.70) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1729964 | 0.92 | F2R (0.58) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1730439 | 0.92 | F2R (0.57) | F2RMAPTKDM4ENPC1RAB9A | |
| Bromide SCHEMBL1731503 | 0.92 | F2R (0.57) | F2RMAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |