Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 13/20 | 0.64 |
| ▸ | CCR6 | P51684 | 7/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20721288 | 0.84 | CCR6 (0.66) | CXCR2CCR6CXCR1 | |
| SCHEMBL13590558 | 0.82 | CXCR2 (0.49) | CXCR2CCR6CXCR1 | |
| SCHEMBL12086733 | 0.78 | CXCR2 (1.00) | CXCR2CCR6CXCR1 | |
| SCHEMBL12087229 | 0.78 | CXCR2 (1.00) | CXCR2CCR6CXCR1 | |
| SCHEMBL12087261 | 0.77 | CXCR2 (1.00) | CXCR2CCR6CXCR1 | |
| SCHEMBL12087214 | 0.74 | CXCR2 (0.95) | CXCR2CCR6CXCR1 | |
| SCHEMBL13479554 | 0.74 | CXCR2 (0.69) | CXCR2CCR6CXCR1 | |
| SCHEMBL13208175 | 0.73 | CXCR2 (0.67) | CXCR2CCR6CXCR1 | |
| SCHEMBL12262520 | 0.72 | CXCR2 (0.93) | CXCR2CCR6CXCR1 | |
| SCHEMBL13406876 | 0.72 | CXCR2 (0.66) | CXCR2CCR6CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1818325-A2 | 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2007-08-15 | — | — | EP | disclosed |