Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047341 | 0.93 | MAPK14 (0.52) | MAPK14KDR | |
| SCHEMBL14452006 | 0.89 | MAPK14 (0.52) | MAPK14KDR | |
| SCHEMBL4049401 | 0.88 | KDR (0.47) | MAPK14KDR | |
| SCHEMBL4048478 | 0.87 | KDR (0.47) | MAPK14KDR | |
| SCHEMBL4052615 | 0.86 | KDR (0.44) | MAPK14KDR | |
| SCHEMBL4047091 | 0.86 | KDR (0.44) | MAPK14KDR | |
| SCHEMBL4043424 | 0.83 | MAPK14 (0.57) | MAPK14KDR | |
| SCHEMBL1459902 | 0.82 | KDR (0.46) | MAPK14KDR | |
| SCHEMBL4048222 | 0.81 | KDR (0.43) | MAPK14KDR | |
| SCHEMBL14469944 | 0.80 | MAPK14 (0.42) | MAPK14KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244733-B2 | Pyrrolotriazine inhibitors of kinases | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-17 | — | — | US | disclosed |