Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 17/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14534583 | 0.89 | CETP (0.79) | CETPKCNH2TLR7VNN1 | |
| SCHEMBL14455285 | 0.89 | CETP (0.77) | CETPKCNH2VNN1 | |
| SCHEMBL14455284 | 0.87 | CETP (0.81) | CETPKCNH2TLR7VNN1 | |
| SCHEMBL14455265 | 0.86 | CETP (0.74) | CETPKCNH2 | |
| SCHEMBL1181808 | 0.86 | CETP (1.00) | CETP | |
| SCHEMBL14455301 | 0.86 | CETP (0.92) | CETPKCNH2TLR7VNN1 | |
| SCHEMBL14455272 | 0.86 | CETP (0.96) | CETPTLR7VNN1 | |
| SCHEMBL14455282 | 0.86 | CETP (0.79) | CETPKCNH2 | |
| SCHEMBL1183218 | 0.86 | CETP (1.00) | CETPTLR7VNN1 | |
| SCHEMBL1182423 | 0.85 | CETP (1.00) | CETPKCNH2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161685-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161685-A1 | HETEROCYCLIC CETP INHIBITORS | CETP, CES1, NPC1 | CETP 1/4885KCNH2 2789/4885TLR7 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.