Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 5/20 | 0.41 |
| ▸ | JAK1 | P23458 | 5/20 | 0.41 |
| ▸ | TYK2 | P29597 | 5/20 | 0.41 |
| ▸ | JAK3 | P52333 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14457086 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1GAAHPGDALOX15 | |
| SCHEMBL14456914 | 0.89 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDALOX15 | |
| SCHEMBL401059 | 0.88 | KDM4E (0.57) | KDM4EALDH1A1GAAHPGDALOX15 | |
| SCHEMBL14457471 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDALOX15 | |
| SCHEMBL399709 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDALOX15 | |
| SCHEMBL399322 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1GAAHPGDALOX15 | |
| Hydrochloric Acid SCHEMBL398556 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1GAAHPGDALOX15 | |
| SCHEMBL13003066 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDALOX15 | |
| SCHEMBL3759456 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1GAAHPGDALOX15 | |
| SCHEMBL398433 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1GAAHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007097981-A2 | ALPHA CARBOLINES AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-08-30 | — | — | WO | disclosed |