Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456964 | 0.88 | CNR1 (0.60) | CYP3A4ALDH1A1NPSR1 | |
| SCHEMBL14456975 | 0.84 | CNR1 (0.60) | CYP3A4ALDH1A1 | |
| SCHEMBL8418285 | 0.83 | CYP3A4 (0.52) | CYP3A4 | |
| SCHEMBL14456974 | 0.83 | CYP3A4 (0.53) | CYP3A4ALDH1A1 | |
| SCHEMBL14456977 | 0.82 | POLB (0.56) | CYP3A4KDM4EALDH1A1HTT | |
| SCHEMBL13391188 | 0.82 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL14456976 | 0.82 | POLB (0.52) | CYP3A4ALDH1A1 | |
| SCHEMBL13003343 | 0.81 | CYP3A4 (0.53) | CYP3A4KCNH2HRH3 | |
| SCHEMBL14456984 | 0.81 | CYP3A4 (0.52) | CYP3A4 | |
| SCHEMBL14456965 | 0.81 | CYP3A4 (0.52) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |