Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836517 | 0.85 | CNR2 (0.37) | CNR2NPC1RAB9ACYP1A2ALOX5AP | |
| SCHEMBL1445808 | 0.75 | CNR2 (0.36) | CNR2NPC1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL3290355 | 0.74 | NPC1 (0.36) | KMT2ACNR2NPC1RAB9ACYP1A2 | |
| SCHEMBL1445669 | 0.72 | CNR2 (0.34) | MEN1KMT2ACNR2NPC1RAB9A | |
| SCHEMBL1445413 | 0.72 | CNR2 (0.39) | CNR2NPC1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL3291100 | 0.72 | CCNB2 (0.36) | CNR2NPC1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL3297481 | 0.71 | CNR2 (0.38) | CNR2NPC1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL3290978 | 0.71 | KDR (0.38) | CNR2NPC1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL6300033 | 0.71 | MAPT (0.49) | MEN1KMT2ANPC1RAB9AKDM4C | |
| SCHEMBL5250541 | 0.71 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9ACREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023706-A1 | PROCESS FOR THE PREPARATION OF A GLUCOKINASE ACTIVATOR COMPOUND | F. HOFFMANN-LA ROCHE AG (CH) | 2011-03-03 | — | — | WO | disclosed |
| US-20110054174-A1 | PROCESS FOR THE PREPARATION OF A GLUCOKINASE ACTIVATOR COMPOUND | HOFFMANN-LA ROCHE, INC. | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054174-A1 | PROCESS FOR THE PREPARATION OF A GLUCOKINASE ACTIVATOR COMPOUND | GCKR, GCK, HK1 | MEN1 2762/4885KMT2A 2741/4885CNR2 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.