Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.47 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531980 | 0.80 | MCHR1 (0.64) | MCHR1MCHR2CYP3A4CYP2C19 | |
| SCHEMBL12531976 | 0.73 | MCHR1 (0.54) | MCHR1MCHR2CYP3A4CYP2C19 | |
| SCHEMBL12545660 | 0.71 | MCHR1 (0.54) | MCHR1MCHR2CYP3A4CYP2C19 | |
| SCHEMBL12532102 | 0.65 | MCHR1 (0.47) | MCHR1MCHR2CYP3A4CYP2C19KCNH2 | |
| SCHEMBL15508851 | 0.65 | MCHR1 (0.60) | MCHR1MCHR2CYP3A4KCNH2 | |
| SCHEMBL16980086 | 0.65 | MCHR1 (0.57) | MCHR1MCHR2CYP3A4KCNH2 | |
| SCHEMBL6069727 | 0.64 | MCHR1 (1.00) | MCHR1MCHR2CYP3A4KCNH2 | |
| SCHEMBL2073311 | 0.64 | MCHR1 (0.58) | MCHR1MCHR2CYP3A4CYP2C19 | |
| SCHEMBL538977 | 0.63 | MCHR1 (0.53) | MCHR1MCHR2CYP3A4CYP2C19KCNH2 | |
| SCHEMBL10144435 | 0.62 | MCHR1 (1.00) | MCHR1CYP3A4CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092416-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |