Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14458061 | 1.00 | MAPT (0.36) | MAPTPTPN1IDO1TDO2 | |
| SCHEMBL3632209 | 0.81 | MAPT (0.36) | MAPTPTPN1IDO1TDO2 | |
| SCHEMBL3158686 | 0.81 | MAPT (0.36) | MAPTPTPN1IDO1TDO2 | |
| SCHEMBL3161230 | 0.81 | MAPT (0.36) | MAPTPTPN1IDO1TDO2 | |
| SCHEMBL3659400 | 0.78 | MAPT (0.34) | MAPT | |
| SCHEMBL3659823 | 0.78 | MAPT (0.34) | MAPT | |
| SCHEMBL5605733 | 0.76 | IDO1 (0.33) | MAPTIDO1TDO2 | |
| SCHEMBL3162292 | 0.76 | IDO1 (0.33) | MAPTIDO1TDO2 | |
| SCHEMBL24898910 | 0.72 | MAPT (0.30) | MAPT | |
| SCHEMBL13479444 | 0.70 | MAPT (0.46) | MAPTPTPN1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247752-B2 | Stereoselectively reducing 2,6,6-trimethyl-2-cyclohexene-1,4-dione with an optically active chiral catalyst to form an optically active hydroxycyclohexenone, contacting the product with a reducing agent to form an optically active diol, and using the diol to form astaxanthin | CARDAX PHARMACEUTICALS, INC. (US) | 2007-07-24 | — | — | US | disclosed |