Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.60 |
| ▸ | GSK3A | P49840 | 13/20 | 0.57 |
| ▸ | SRC | P12931 | 15/20 | 0.57 |
| ▸ | SYK | P43405 | 15/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14459485 | 0.91 | MAPK14 (0.60) | MAPK14GSK3ASRCSYK | |
| SCHEMBL6298751 | 0.88 | GSK3A (0.67) | MAPK14GSK3ASRCSYK | |
| SCHEMBL5249388 | 0.88 | MAPK14 (0.49) | MAPK14GSK3ASRCSYK | |
| SCHEMBL14459482 | 0.86 | GSK3A (0.68) | MAPK14GSK3ASRCSYK | |
| SCHEMBL6840076 | 0.86 | GSK3A (0.67) | MAPK14GSK3ASRCSYK | |
| SCHEMBL6547129 | 0.85 | MAPK14 (0.59) | MAPK14GSK3ASRCSYK | |
| SCHEMBL6545894 | 0.84 | MAPK14 (0.59) | MAPK14GSK3ASRCSYK | |
| SCHEMBL14459484 | 0.83 | GSK3A (0.62) | MAPK14GSK3ASRCSYK | |
| SCHEMBL6545663 | 0.82 | GSK3A (0.70) | MAPK14GSK3ASRCSYK | |
| SCHEMBL6546013 | 0.81 | GSK3A (0.69) | MAPK14GSK3ASRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241758-B2 | Compounds useful as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241758-B2 | Compounds useful as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-07-10 | — | — | US | disclosed |