Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585880 | 0.90 | STAT3 (0.41) | STAT3STAT1 | |
| Hydrochloric Acid SCHEMBL583840 | 0.90 | STAT3 (0.40) | STAT3STAT1TERT | |
| SCHEMBL10084843 | 0.90 | STAT3 (0.40) | STAT3STAT1 | |
| SCHEMBL29395084 | 0.86 | STAT3 (0.50) | STAT3STAT1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL585267 | 0.86 | STAT3 (0.43) | STAT3STAT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12427957 | 0.86 | STAT3 (0.43) | STAT3STAT1ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL584869 | 0.85 | STAT3 (0.43) | STAT3STAT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14449211 | 0.85 | STAT3 (0.43) | STAT3STAT1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28879055 | 0.85 | STAT3 (0.49) | STAT3STAT1MEN1KMT2ASMN1; SMN2 | |
| Exeporfinium SCHEMBL585997 | 0.85 | STAT3 (0.52) | STAT3STAT1SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244841-B2 | Porphyrin derivatives and their use in photodynamic therapy | DESTINY PHARMA LIMITED (GB) | 2007-07-17 | — | — | US | disclosed |