Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 7/20 | 0.55 |
| ▸ | MTTP | P55157 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12174442 | 0.94 | NPY2R (0.56) | NPY2RMTTPKDM4EGAASMN1; SMN2 | |
| SCHEMBL14463109 | 0.85 | NPY2R (0.66) | NPY2RMTTP | |
| SCHEMBL2583429 | 0.83 | MTTP (0.59) | NPY2RMTTP | |
| SCHEMBL12174536 | 0.82 | MTTP (0.53) | NPY2RMTTP | |
| SCHEMBL13084991 | 0.82 | NPY2R (0.60) | NPY2RMTTPGAASMN1; SMN2 | |
| SCHEMBL12174450 | 0.82 | MTTP (0.54) | NPY2RMTTP | |
| SCHEMBL12157625 | 0.81 | NPY2R (0.55) | NPY2RMTTPKDM4E | |
| SCHEMBL12174534 | 0.81 | MTTP (0.49) | NPY2RMTTPMAPTKDM4EGAA | |
| SCHEMBL12174403 | 0.80 | MTTP (0.55) | NPY2RMTTP | |
| SCHEMBL14463105 | 0.80 | MTTP (0.53) | NPY2RMTTPMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806341-A2 | (+)Phenyl-(4-{4-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-phenyl}-piperidin-1-yl)-acetic acid methyl ester as lipid lowering agent | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-11 | — | — | EP | disclosed |