Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.78 |
| ▸ | PTGER3 | P43115 | 9/20 | 0.65 |
| ▸ | PTGER2 | P43116 | 9/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5220323 | 0.90 | PTGER4 (0.82) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5220327 | 0.90 | PTGER4 (0.82) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5220316 | 0.90 | PTGER4 (0.82) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5216931 | 0.87 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6616568 | 0.87 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5215108 | 0.87 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5215102 | 0.87 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5215114 | 0.87 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5215117 | 0.87 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5216123 | 0.87 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408961-B1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | HOFFMANN LA ROCHE (CH) | 2007-07-11 | — | — | EP | disclosed |