Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 11/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13992370 | 0.87 | HMGCR (0.61) | HMGCR | |
| SCHEMBL8571000 | 0.83 | HMGCR (0.71) | HMGCR | |
| SCHEMBL8321853 | 0.83 | HMGCR (0.71) | HMGCR | |
| SCHEMBL10661873 | 0.83 | HMGCR (0.71) | HMGCR | |
| SCHEMBL9023237 | 0.77 | HMGCR (0.85) | HMGCR | |
| SCHEMBL9022402 | 0.77 | HMGCR (0.85) | HMGCR | |
| SCHEMBL13994086 | 0.77 | HMGCR (0.61) | HMGCR | |
| SCHEMBL13992367 | 0.76 | HMGCR (0.49) | HMGCR | |
| SCHEMBL10665630 | 0.76 | HMGCR (0.66) | HMGCR | |
| SCHEMBL10662722 | 0.76 | HMGCR (0.66) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1810971-A1 | Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia | SCHERING CORPORATION (US) | 2007-07-25 | — | — | EP | disclosed |