SCHEMBL14464464

SCHEMBL14464464

O=C(O)c1ccc(OCCOC2=CC=C(OCCCCOc3ccccc3)CC2)c(C(=O)NC2CCCC(C(=O)O)C2)c1

nearest known ligand 0.78

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 2/20 0.78
POLB P06746 3/20 0.44
CASP6 P55212 1/20 0.44
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 3/20 0.38
PKM P14618 3/20 0.38
NPC1 O15118 1/20 0.38
EPHX2 P34913 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SGMS2 Q8NHU3 1/20 0.38
CYSLTR1 Q9Y271 1/20 0.38
GRM5 P41594 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4527632 0.94 CYSLTR2 (0.88) CYSLTR2POLBCASP6MEN1KMT2A
SCHEMBL13932996 0.89 CYSLTR2 (0.98) CYSLTR2POLBCASP6MEN1KMT2A
SCHEMBL4512506 0.88 CYSLTR2 (1.00) CYSLTR2POLBCASP6MEN1KMT2A
SCHEMBL29438768 0.88 CYSLTR2 (1.00) CYSLTR2POLBCASP6MEN1KMT2A
SCHEMBL4527529 0.87 CYSLTR2 (0.95) CYSLTR2POLBCASP6MEN1KMT2A
SCHEMBL4518299 0.85 CYSLTR2 (0.74) CYSLTR2POLBCASP6ALDH1A1PKM
SCHEMBL4518296 0.85 CYSLTR2 (0.74) CYSLTR2POLBCASP6ALDH1A1PKM
SCHEMBL4533390 0.84 CYSLTR2 (0.75) CYSLTR2POLBCASP6MEN1KMT2A
SCHEMBL4526257 0.84 CYSLTR2 (0.77) CYSLTR2POLBCASP6MEN1KMT2A
SCHEMBL4522489 0.83 CYSLTR2 (0.73) CYSLTR2POLBCASP6NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1572628-B1 ISOPHTALIC ACID DERIVATIVES BAYER HEALTHCARE AG (DE) 2007-07-25 EP disclosed