Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2082270 | 0.80 | MAPT (0.55) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL2082273 | 0.80 | MAPT (0.55) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL12785434 | 0.77 | BACE1 (0.41) | BACE1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL12784443 | 0.73 | MAPT (0.50) | MAPTALDH1A1KDM4EL3MBTL1MAOB | |
| SCHEMBL14464924 | 0.69 | TBXA2R (0.38) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL27785602 | 0.67 | MAPT (0.42) | MAPTALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL1193410 | 0.67 | MAPT (0.65) | BACE1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL1193408 | 0.67 | MAPT (0.65) | BACE1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL2079090 | 0.67 | MAPT (0.55) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL2079088 | 0.67 | MAPT (0.55) | MAPTALDH1A1KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084450-A2 | CANNIBINOID RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |