Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13039139 | 0.86 | IGF1R (0.75) | IGF1R | |
| SCHEMBL1879416 | 0.84 | IGF1R (0.64) | IGF1R | |
| SCHEMBL1876707 | 0.84 | IGF1R (0.75) | IGF1R | |
| SCHEMBL13039117 | 0.79 | IGF1R (0.73) | IGF1R | |
| SCHEMBL2940331 | 0.79 | IGF1R (0.72) | IGF1R | |
| SCHEMBL2939981 | 0.79 | IGF1R (1.00) | IGF1R | |
| SCHEMBL6176176 | 0.79 | IGF1R (0.67) | IGF1R | |
| SCHEMBL13904047 | 0.79 | IGF1R (0.72) | IGF1R | |
| SCHEMBL31573011 | 0.79 | IGF1R (0.75) | IGF1R | |
| SCHEMBL2933891 | 0.79 | IGF1R (0.78) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007083017-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2007-07-26 | — | — | WO | disclosed |