SCHEMBL1446574

SCHEMBL1446574

NNc1ccc([N+](=O)[O-])cn1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.60
MEN1 O00255 8/20 0.60
MAPT P10636 7/20 0.60
GAA P10253 2/20 0.60
LMNA P02545 2/20 0.60
CYP1A2 P05177 1/20 0.60
ALOX12 P18054 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.55
POLB P06746 1/20 0.55
PABPC1 P11940 1/20 0.54
RAB9A P51151 7/20 0.53
NPC1 O15118 5/20 0.53
ALDH1A1 P00352 3/20 0.53
PKM P14618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31503950 1.00 KMT2A (0.60) KMT2AMEN1MAPTGAALMNA
Hydrochloric Acid SCHEMBL3117154 0.98 KMT2A (0.58) KMT2AMEN1MAPTGAALMNA
SCHEMBL11156040 0.86 MAPT (0.60) KMT2AMEN1MAPTGAALMNA
SCHEMBL20796131 0.84 MEN1 (0.74) KMT2AMEN1MAPTGAALMNA
SCHEMBL3943376 0.82 MEN1 (0.62) KMT2AMEN1MAPTGAALMNA
SCHEMBL8503181 0.81 KMT2A (0.60) KMT2AMEN1MAPTGAALMNA
SCHEMBL18469873 0.81 KMT2A (0.60) KMT2AMEN1MAPTGAALMNA
SCHEMBL930847 0.81 GAA (0.65) KMT2AMEN1MAPTGAALMNA
SCHEMBL5528679 0.81 GAA (0.65) KMT2AMEN1MAPTGAALMNA
SCHEMBL8503182 0.81 KMT2A (0.60) KMT2AMEN1MAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116987076-A 1,2, 4-triazolo [4,3-a ] pyridine sulfone derivative, and preparation method and application thereof 贵州大学 2023-11-03 CN claimed
CN-108484583-B Colorimetric method for detecting Cu in water2+And Ni2+Synthesis and application of probe 湖南师范大学 2021-03-02 CN claimed
CN-108484583-A Cu in a kind of colorimetric determination water2+And Ni2+The synthesis and application of probe 湖南师范大学 2018-09-04 CN claimed
US-20260146049-A1 SPIROCYCLIC ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2026-05-28 US disclosed
WO-2024217557-A1 SUBSTITUTED TETRAHYDROFURANS AS NAV1.8 INHIBITORS 武汉人福创新药物研发中心有限公司 2024-10-24 WO disclosed
CN-118812519-A Substituted tetrahydrofurans as Nav1.8 inhibitors 武汉人福创新药物研发中心有限公司 2024-10-22 CN disclosed
CN-114437062-B Compound capable of being used as sodium channel regulator and application thereof 成都海博为药业有限公司 2024-05-17 CN disclosed
CN-116987076-A 1,2, 4-triazolo [4,3-a ] pyridine sulfone derivative, and preparation method and application thereof 贵州大学 2023-11-03 CN disclosed
CN-116693394-A Dehydrazine method and application 大连理工大学 2023-09-05 CN disclosed
WO-2023091726-A1 INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) SYROS PHARMACEUTICALS, INC. (US) 2023-05-25 WO disclosed
US-11492366-B2 Platinum compounds for binding guanine quadruplexes QUEEN'S UNIVERSITY AT KINGSTON 2022-11-08 US disclosed
US-4663327-A MICROBIOCIDES, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1987-05-05 US disclosed
EP-0201892-A1 Method of making azo compounds BAYER AG (DE) 1986-11-20 EP disclosed
EP-0087446-B1 METHOD OF FORMING A PHOTOGRAPHIC DYE IMAGE KODAK LIMITED (GB) 1986-07-09 EP disclosed
US-4481268-A METALLIZED AZO OR AZO-METHINE DYES EASTMAN KODAK COMPANY (US) 1984-11-06 US disclosed
EP-0087446-A1 METHOD OF FORMING A PHOTOGRAPHIC DYE IMAGE. KODAK LTD (GB) 1983-09-07 EP disclosed
WO-1983000939-A1 METHOD OF FORMING A PHOTOGRAPHIC DYE IMAGE BAILEY, JOSEPH 1983-03-17 WO disclosed
US-4165238-A DIFFUSION TRANSFER, BALLASTED, METALLIZED EASTMAN KODAK COMPANY (US) 1979-08-21 US disclosed
US-4147544-A Photographic products and processes employing novel nondiffusible pyridylazonaphthol dye-releasing compounds EASTMAN KODAK COMPANY (US) 1979-04-03 US disclosed
US-4121035-A 5-Amino-2-hydrazinopyridine and derivatives thereof MORTON-NORWICH PRODUCTS, INC. (US) 1978-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492366-B2 Platinum compounds for binding guanine quadruplexes PCNA, DDB1, SERBP1 KMT2A 2676/4885MEN1 1632/4885MAPT 2215/4885
US-20260146049-A1 SPIROCYCLIC ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER KRAS, NRAS, HRAS KMT2A 2363/4885MEN1 646/4885MAPT 4833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.