Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14467869 | 0.97 | SGK1 (0.40) | SGK1HRH3MAP2K4GRM4SOS1 | |
| SCHEMBL13052752 | 0.96 | SGK1 (0.41) | SGK1HRH3MAP2K4PIK3CAMTOR | |
| SCHEMBL13051962 | 0.92 | SGK1 (0.39) | SGK1MAP2K4PIK3CAMTORBRPF1 | |
| SCHEMBL13051639 | 0.91 | SGK1 (0.40) | SGK1MAP2K4PIK3CAMTORBRPF1 | |
| SCHEMBL13051637 | 0.90 | SGK1 (0.41) | SGK1MAP2K4PIK3CAMTORBRPF1 | |
| SCHEMBL13051578 | 0.89 | SGK1 (0.39) | SGK1HRH3MAP2K4PIK3CAMTOR | |
| SCHEMBL12995299 | 0.88 | HRH3 (0.35) | SGK1HRH3MAP2K4SOS1ALK | |
| SCHEMBL13051630 | 0.86 | HRH3 (0.34) | HRH3DUTS1PR3 | |
| SCHEMBL13053255 | 0.86 | HRH3 (0.35) | HRH3 | |
| SCHEMBL13052788 | 0.86 | SGK1 (0.38) | SGK1MAP2K4PIK3CAMTORBRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |