Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 17/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14449123 | 1.00 | F2R (0.44) | F2RLMNACYP3A4ALDH1A1GAA | |
| SCHEMBL14469095 | 0.95 | F2R (0.40) | F2RLMNA | |
| SCHEMBL14449164 | 0.95 | F2R (0.40) | F2RLMNA | |
| SCHEMBL14469068 | 0.91 | F2R (0.40) | F2R | |
| SCHEMBL14449173 | 0.91 | F2R (0.40) | F2R | |
| SCHEMBL14449178 | 0.89 | F2R (0.39) | F2R | |
| SCHEMBL14469076 | 0.89 | F2R (0.57) | F2R | |
| SCHEMBL14449175 | 0.89 | F2R (0.57) | F2R | |
| Trifluoroacetic Acid SCHEMBL1729328 | 0.86 | F2R (0.51) | F2RLMNA | |
| Bromide SCHEMBL1730631 | 0.86 | F2R (0.52) | F2RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |