SCHEMBL1446914

SCHEMBL1446914

CCCCCCCc1ccnc(-c2cc(CCCCCCC)ccn2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PTGS2 P35354 3/20 0.46
ESR1 P03372 2/20 0.46
ADRA2A P08913 2/20 0.46
ADORA3 P0DMS8 2/20 0.46
TACR2 P21452 2/20 0.46
SLC6A2 P23975 2/20 0.46
SLC6A4 P31645 2/20 0.46
SLC6A3 Q01959 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
LMNA P02545 1/20 0.46
SHBG P04278 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
HSPD1 P10809 1/20 0.46
ADRB3 P13945 1/20 0.46
HTR2C P28335 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL913268 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A
SCHEMBL31004368 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A
SCHEMBL4863242 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A
SCHEMBL529596 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A
SCHEMBL913250 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A
SCHEMBL11798255 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A
SCHEMBL29427461 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A
SCHEMBL7964430 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A
SCHEMBL7963811 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A
SCHEMBL5079241 1.00 TDP1 (0.46) TDP1L3MBTL1PTGS2ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106622-B Aqueous dispersion coating 浙江省化工研究院有限公司 2022-09-06 CN claimed
CN-114106622-A Aqueous dispersion coating 浙江省化工研究院有限公司 2022-03-01 CN claimed
JP-2001507372-A 2001-06-05 JP claimed
EP-0981559-A1 IMPROVED METHOD OF MAKING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2000-03-01 EP claimed
EP-0977540-A1 PERSONAL CARE COMPOSITIONS CONTAINING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2000-02-09 EP claimed
US-5986015-A REACTION OF MONOMERS BY COPOLYMERIZATION AND WITH AN ORGANIC HALIDE IN THE PRESENCE OF COPPER SALT TO FORM GRAFT POLYMER THE PROCTER & GAMBLE COMPANY (US) 1999-11-16 US claimed
WO-1998051261-A1 PERSONAL CARE COMPOSITIONS CONTAINING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 1998-11-19 WO claimed
WO-1998051722-A1 IMPROVED METHOD OF MAKING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 1998-11-19 WO claimed
US-20230133542-A1 METHOD FOR PRODUCING POROUS BASE MATERIAL HAVING PORE WITH SURFACE MODIFIED AND POROUS BASE MATERIAL HAVING PORE WITH SURFACE MODIFIED NITTO DENKO CORPORATION (JP) 2023-05-04 US disclosed
WO-2023042665-A1 COMPOSITE BASE MATERIAL AND MANUFACTURING METHOD THEREOF 日東電工株式会社 2023-03-23 WO disclosed
WO-2023042666-A1 COMPOSITE BASE MATERIAL AND METHOD FOR PRODUCING SAME 日東電工株式会社 2023-03-23 WO disclosed
CN-114106622-B Aqueous dispersion coating 浙江省化工研究院有限公司 2022-09-06 CN disclosed
CN-114106622-A Aqueous dispersion coating 浙江省化工研究院有限公司 2022-03-01 CN disclosed
US-11117996-B2 Self-assembly composition for pattern formation and pattern forming method Oji Holdings Corporation (JP) 2021-09-14 US disclosed
US-5986015-A REACTION OF MONOMERS BY COPOLYMERIZATION AND WITH AN ORGANIC HALIDE IN THE PRESENCE OF COPPER SALT TO FORM GRAFT POLYMER THE PROCTER & GAMBLE COMPANY (US) 1999-11-16 US disclosed
WO-1999054365-A1 REMOVAL OF HALOGENS FROM POLYMERIZATION PRODUCT AND THE REDUCED HALOGEN POLYMER AND METHOD PPG INDUSTRIES OHIO, INC. (US) 1999-10-28 WO disclosed
WO-1998051722-A1 IMPROVED METHOD OF MAKING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 1998-11-19 WO disclosed
US-5807937-A Processes based on atom (or group) transfer radical polymerization and novel (co) polymers having useful structures and properties CARNEGIE MELLON UNIVERSITY (US) 1998-09-15 US disclosed
EP-0861272-A1 IMPROVED PROCESSES BASED ON ATOM (OR GROUP) TRANSFER RADICAL POLYMERIZATION AND NOVEL (CO)POLYMERS HAVING USEFUL STRUCTURES AND PROPERTIES CARNEGIE MELLON UNIVERSITY (US) 1998-09-02 EP disclosed
WO-1997018247-A1 IMPROVED PROCESSES BASED ON ATOM (OR GROUP) TRANSFER RADICAL POLYMERIZATION AND NOVEL (CO)POLYMERS HAVING USEFUL STRUCTURES AND PROPERTIES CARNEGIE MELLON UNIVERSITY (US) 1997-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11117996-B2 Self-assembly composition for pattern formation and pattern forming method IAPP, SAMM50, MAN1B1 TDP1 1883/4885L3MBTL1 4746/4885PTGS2 3809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.