Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 1.00 |
| ▸ | YES1 | P07947 | 5/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.49 |
| ▸ | ABL1 | P00519 | 3/20 | 0.49 |
| ▸ | LCK | P06239 | 3/20 | 0.49 |
| ▸ | LYN | P07948 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | CSK | P41240 | 1/20 | 0.49 |
| ▸ | BLK | P51451 | 1/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | TEK | Q02763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4268846 | 0.95 | SRC (0.91) | SRCYES1PDGFRBEPHB4ABL1 | |
| SCHEMBL13609693 | 0.93 | SRC (1.00) | SRCYES1PDGFRBEPHB4ABL1 | |
| SCHEMBL4265047 | 0.81 | SRC (1.00) | SRCYES1PDGFRBEPHB4ABL1 | |
| SCHEMBL4267558 | 0.79 | SRC (1.00) | SRCYES1PDGFRBEPHB4ABL1 | |
| SCHEMBL4268527 | 0.75 | SRC (1.00) | SRCYES1PDGFRBEPHB4ABL1 | |
| SCHEMBL4272365 | 0.73 | SRC (1.00) | SRCYES1PDGFRBEPHB4 | |
| SCHEMBL4273143 | 0.71 | SRC (0.77) | SRCYES1PDGFRBEPHB4ABL1 | |
| SCHEMBL4265948 | 0.69 | SRC (1.00) | SRCYES1PDGFRBEPHB4ABL1 | |
| SCHEMBL4264260 | 0.68 | SRC (1.00) | SRCYES1PDGFRBEPHB4ABL1 | |
| SCHEMBL4266596 | 0.68 | SRC (1.00) | SRCYES1PDGFRBEPHB4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2543376-A1 | Benzotriazine inhibitors of kinases | Targegen, Inc. (US) | 2013-01-09 | — | — | EP | disclosed |