Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14471995 | 0.92 | TLR7 (0.86) | TLR7TLR8 | |
| SCHEMBL2849174 | 0.92 | TLR7 (1.00) | TLR7 | |
| SCHEMBL14472181 | 0.89 | TLR7 (0.88) | TLR7TLR8 | |
| SCHEMBL14472197 | 0.86 | TLR7 (0.86) | TLR7 | |
| SCHEMBL14472037 | 0.86 | TLR7 (0.84) | TLR7TLR8 | |
| SCHEMBL2846064 | 0.86 | TLR7 (0.88) | TLR7 | |
| SCHEMBL14472152 | 0.85 | TLR7 (0.88) | TLR7 | |
| SCHEMBL2854653 | 0.85 | TLR7 (1.00) | TLR7 | |
| SCHEMBL2846786 | 0.84 | TLR7 (0.84) | TLR7TLR8 | |
| SCHEMBL14472189 | 0.84 | TLR7 (0.87) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222648-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS | ASTRAZENECA AB (SE) | 2013-01-09 | — | — | EP | claimed |