Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.59 |
| ▸ | AXL | P30530 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14475168 | 0.88 | PIK3CA (0.49) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL14475072 | 0.87 | MAP4K4 (0.53) | MEN1MAP4K4ABCG2ADORA2AADORA1 | |
| SCHEMBL14474998 | 0.87 | ABCG2 (0.55) | MAP4K4ABCG2ADORA2AADORA1PIK3CA | |
| SCHEMBL14475050 | 0.86 | CYP1A2 (0.54) | MEN1MAP4K4ABCG2ADORA2AADORA1 | |
| SCHEMBL14475029 | 0.86 | PDE5A (0.51) | MEN1MAP4K4ABCG2ADORA2AADORA1 | |
| SCHEMBL14475229 | 0.84 | CYP1A2 (0.64) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL20273750 | 0.84 | CYP1A2 (0.64) | MEN1PSIP1AXLMKNK1MKNK2 | |
| SCHEMBL14727934 | 0.84 | ABCG2 (0.61) | MEN1MAP4K4ABCG2CYP1A2CYP3A4 | |
| SCHEMBL14727837 | 0.84 | ABCG2 (0.56) | MEN1MAP4K4ABCG2ADORA2AADORA1 | |
| SCHEMBL18023076 | 0.84 | POLB (0.49) | MEN1MAP4K4ABCG2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013003586-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-03 | — | — | WO | disclosed |