Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 13/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14727307 | 0.87 | ABCG2 (0.56) | ABCG2USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL14727326 | 0.86 | ABCG2 (0.57) | ABCG2USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL14474010 | 0.83 | ABCG2 (0.54) | ABCG2USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL16183325 | 0.81 | ABCG2 (0.58) | ABCG2USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL14727305 | 0.81 | ABCG2 (0.65) | ABCG2USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL14475475 | 0.78 | ABCG2 (0.52) | ABCG2USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL2154960 | 0.78 | ABCG2 (0.63) | ABCG2USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL16183342 | 0.78 | ABCG2 (0.63) | ABCG2USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL14474543 | 0.78 | ABCG2 (0.65) | ABCG2USP2LMNACYP1A2CYP3A4 | |
| SCHEMBL14474151 | 0.77 | ABCG2 (0.53) | ABCG2LMNAABCB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013003586-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-03 | — | — | WO | disclosed |