SCHEMBL14477446

SCHEMBL14477446

ClC1(Cl)CC(Cl)(Cl)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3158869 0.67
SCHEMBL318754 0.67
SCHEMBL14401791 0.67
SCHEMBL988025 0.67
Hydrochloric Acid SCHEMBL21855056 0.62
SCHEMBL1038139 0.59
SCHEMBL11683648 0.59
SCHEMBL11239430 0.56
SCHEMBL290742 0.56
Hydrochloric Acid SCHEMBL21855077 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585511-B1 ASTHMA AND ALLERGIC INFLAMMATION MODULATORS AMGEN INC (US) 2013-01-23 EP disclosed
US-20130012506-A1 ANTI-INFECTIVE PYRIDO (1,2-A) PYRIMIDINES NO ZAESUNG (KR) 2013-01-10 US disclosed
WO-2013001830-A1 NUCLEOSIDE ANTIBIOTIC DERIVATIVE 国立大学法人北海道大学 (JP) 2013-01-03 WO disclosed
US-20070112200-A1 Non-racemic hexafluoreleucine,and methods of making and using it TRUSTEES OF TUFTS COLLEGE (US) 2007-05-17 US disclosed
US-20070072862-A1 Bis-aryl amide compounds and methods of use AMGEN INC. 2007-03-29 US disclosed
WO-2007015757-A2 INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR-A MODULATORS; SYNTHESES OF SUCH MODULATORS AND METHODS OF USING SUCH MODULATORS NEREUS PHARMACEUTICALS, INC. (US) 2007-02-08 WO disclosed