Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | CA2 | P00918 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858896 | 1.00 | GRK6 (0.54) | GRK6CA1CA2TSHRNPC1 | |
| SCHEMBL13399023 | 1.00 | GRK6 (0.54) | GRK6CA1CA2TSHRNPC1 | |
| SCHEMBL14353366 | 1.00 | GRK6 (0.54) | GRK6CA1CA2TSHRNPC1 | |
| SCHEMBL14478532 | 0.87 | GRK6 (0.55) | GRK6CA1CA2TSHRNPC1 | |
| SCHEMBL14353191 | 0.87 | GRK6 (0.55) | GRK6CA1CA2TSHRNPC1 | |
| SCHEMBL14353232 | 0.85 | CA1 (0.64) | GRK6CA1CA2TSHRNPC1 | |
| SCHEMBL14478587 | 0.85 | CA1 (0.64) | GRK6CA1CA2TSHRNPC1 | |
| SCHEMBL9399690 | 0.85 | CA1 (0.64) | GRK6CA1CA2TSHRNPC1 | |
| SCHEMBL15563047 | 0.79 | NPC1 (0.56) | CA1CA2TSHRNPC1RAB9A | |
| SCHEMBL15563398 | 0.79 | NPC1 (0.56) | CA1CA2TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130004979-A1 | GLYCOSYLTRANSFERASE REVERSIBILITY FOR SUGAR NUCLEOTIDE SYNTHESIS AND MICROSCALE SCANNING | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-03 | — | — | US | disclosed |