Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1448374 | 1.00 | KMT2A (0.71) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL1448369 | 1.00 | KMT2A (0.71) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL16378708 | 0.85 | NPC1 (0.48) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL15128379 | 0.81 | KMT2A (0.59) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL469831 | 0.81 | KMT2A (0.71) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL4900001 | 0.81 | KMT2A (0.71) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL29997656 | 0.81 | KMT2A (0.71) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL2695442 | 0.79 | KMT2A (0.68) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL15053133 | 0.79 | KMT2A (0.68) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL2314861 | 0.79 | KMT2A (0.68) | KMT2AMEN1NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373758-B1 | PHOTOCHROMIC OPTICAL ARTICLES PREPARED WITH REVERSIBLE THERMOCHROMIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2017-05-10 | — | — | EP | disclosed |
| US-20140225027-A1 | Silver Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW CORNING CORPORATION | 2014-08-14 | — | — | US | disclosed |
| US-8547625-B2 | Photochromic optical articles prepared with reversible thermochromic materials | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| EP-2373758-A1 | PHOTOCHROMIC OPTICAL ARTICLES PREPARED WITH REVERSIBLE THERMOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2011-10-12 | — | — | EP | disclosed |
| US-7911676-B2 | Photochromic optical articles prepared with reversible thermochromic materials | TRANSITIONS OPTICAL, INC. (US) | 2011-03-22 | — | — | US | disclosed |
| US-20110051223-A1 | PHOTOCHROMIC OPTICAL ARTICLES PREPARED WITH REVERSIBLE THERMOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (FL) | 2011-03-03 | — | — | US | disclosed |
| WO-2010074969-A1 | PHOTOCHROMIC OPTICAL ARTICLES PREPARED WITH REVERSIBLE THERMOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| US-20100149620-A1 | PHOTOCHROMIC OPTICAL ARTICLES PREPARED WITH REVERSIBLE THERMOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140225027-A1 | Silver Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | ALG8, GYPA, HIRA | KMT2A 1384/4885MEN1 1927/4885NPC1 2820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.