Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.85 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.85 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.85 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | RAB9A | P51151 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.79 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.79 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.78 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.78 |
| ▸ | USP2 | O75604 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | CA1 | P00915 | 2/20 | 0.74 |
| ▸ | CA2 | P00918 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485374 | 0.96 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL14497556 | 0.96 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL30132731 | 0.96 | GPBAR1 (0.83) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL19577573 | 0.95 | GPBAR1 (0.81) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL17430857 | 0.95 | GPBAR1 (0.81) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL19577558 | 0.95 | GPBAR1 (0.81) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL23312348 | 0.95 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL1653681 | 0.95 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL20375456 | 0.95 | GPBAR1 (0.80) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A | |
| SCHEMBL15467319 | 0.95 | GPBAR1 (0.85) | GPBAR1SLC10A2SLC10A1ABCB11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235678-B2 | Bile acid derived steroidal dimers with novel amphiphilic topology having antifungal activity | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-26 | — | — | US | disclosed |