SCHEMBL14488604

SCHEMBL14488604

OCc1ccc(N(c2ccccc2)c2ccc(N(c3ccccc3)c3ccc(CO)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
ALDH1A1 P00352 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
LTA4H P09960 1/20 0.50
NR1I2 O75469 1/20 0.44
CRHBP P24387 1/20 0.42
ATM Q13315 1/20 0.42
CRHR2 Q13324 1/20 0.42
TLR9 Q9NR96 1/20 0.42
VHL P40337 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439584 1.00 TSHR (0.59) TSHRMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL279125 1.00 TSHR (0.59) TSHRMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL14174076 1.00 TSHR (0.59) TSHRMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL13599812 0.94 TSHR (0.52) TSHRMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL10330866 0.94 TSHR (0.52) TSHRMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL14173670 0.94 TSHR (0.52) TSHRMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL22941864 0.94 TSHR (0.52) TSHRMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL14174075 0.94 TSHR (0.52) TSHRMEN1KMT2AALDH1A1L3MBTL1
Benzyl Alcohol SCHEMBL28301197 0.93 TSHR (0.70) TSHRMEN1KMT2AALDH1A1L3MBTL1
SCHEMBL14489067 0.92 TSHR (0.50) TSHRMEN1KMT2AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9529291-B2 Image forming apparatus and image forming method FUJI XEROX CO., LTD. (JP) 2016-12-27 US disclosed
US-20160349639-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD FUJI XEROX CO., LTD. (JP) 2016-12-01 US disclosed
US-7229729-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MONOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-06-12 US disclosed
US-7229729-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MONOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-06-12 US disclosed