Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 1.00 |
| ▸ | PLAT | P00750 | 1/20 | 0.66 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.66 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502373 | 1.00 | F10 (1.00) | F10PLATKLKB1F2 | |
| SCHEMBL14502117 | 0.99 | F10 (1.00) | F10PLATKLKB1F2 | |
| SCHEMBL1995123 | 0.99 | F10 (1.00) | F10PLATKLKB1F2 | |
| SCHEMBL14490698 | 0.99 | F10 (1.00) | F10PLATKLKB1F2 | |
| SCHEMBL14490708 | 0.98 | F10 (0.98) | F10PLATKLKB1F2 | |
| SCHEMBL14525003 | 0.98 | F10 (0.98) | F10PLATKLKB1F2 | |
| SCHEMBL2000084 | 0.97 | F10 (1.00) | F10PLATKLKB1F2 | |
| SCHEMBL14490689 | 0.97 | F10 (1.00) | F10PLATKLKB1F2 | |
| SCHEMBL14501913 | 0.96 | F10 (1.00) | F10PLATKLKB1 | |
| SCHEMBL14490710 | 0.96 | F10 (1.00) | F10PLATKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135428-A1 | LACTAM CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | QIAO JENNIFER X | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135428-A1 | LACTAM CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | F12, F2, PEPD | F10 53/4885PLAT 33/4885KLKB1 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.