SCHEMBL14490751

SCHEMBL14490751

O=C(NC1CCCC[C@@H]1NC(=O)c1ccc(-n2ccccc2=O)cc1)c1ccc2cc(Cl)ccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1998914 1.00 F10 (1.00) F10
SCHEMBL14501916 1.00 F10 (1.00) F10
SCHEMBL14490794 0.98 F10 (1.00) F10
SCHEMBL2000074 0.98 F10 (1.00) F10
SCHEMBL14502195 0.90 F10 (1.00) F10
SCHEMBL14490718 0.90 F10 (1.00) F10
SCHEMBL14502119 0.88 F10 (0.80) F10
SCHEMBL5436250 0.88 F10 (0.80) F10
SCHEMBL14490709 0.88 F10 (0.80) F10
SCHEMBL5436247 0.88 F10 (0.80) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070135428-A1 LACTAM CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS QIAO JENNIFER X 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135428-A1 LACTAM CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS F12, F2, PEPD F10 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.