Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24984732 | 0.85 | TNF (0.54) | CYP19A1CYP1A2CYP2C19CHRNEMEN1 | |
| SCHEMBL28230447 | 0.85 | MEN1 (0.60) | CYP19A1CHRNEMEN1KMT2AP2RX4 | |
| SCHEMBL30616063 | 0.84 | CHRNE (0.63) | CYP19A1CYP1A2CYP2C19CHRNEMEN1 | |
| SCHEMBL29093444 | 0.84 | CHRNE (0.63) | CYP19A1CYP1A2CYP2C19CHRNEMEN1 | |
| SCHEMBL24625817 | 0.79 | CYP19A1 (0.48) | CYP19A1CYP1A2CYP2C19CHRNEMEN1 | |
| SCHEMBL14492829 | 0.79 | CYP19A1 (0.61) | CYP19A1CYP1A2CYP2C19P2RX4ALDH1A1 | |
| SCHEMBL14492832 | 0.77 | CYP19A1 (0.59) | CYP19A1CYP1A2CYP2C19CHRNEP2RX4 | |
| SCHEMBL18406152 | 0.76 | CHRNE (0.42) | CYP19A1CYP1A2CYP2C19CHRNEMEN1 | |
| SCHEMBL21154987 | 0.75 | CYP19A1 (0.44) | CYP19A1CYP1A2CYP2C19CHRNEMEN1 | |
| SCHEMBL17943386 | 0.74 | CYP19A1 (0.62) | CYP19A1CYP1A2CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7227027-B2 | Carbazole derivative and its use in electroluminescent devices | TSINGHUA UNIVERSITY (CH) | 2007-06-05 | — | — | US | disclosed |
| US-7227027-B2 | Carbazole derivative and its use in electroluminescent devices | TSINGHUA UNIVERSITY (CH) | 2007-06-05 | — | — | US | disclosed |