Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496461 | 0.88 | F10 (0.44) | F10KLKB1KCNH2TP53TSHR | |
| SCHEMBL14514659 | 0.87 | F10 (0.36) | F10KLKB1KCNH2 | |
| SCHEMBL14496477 | 0.86 | F10 (0.43) | F10KLKB1KCNH2TP53TSHR | |
| SCHEMBL14496429 | 0.86 | F10 (0.44) | F10KLKB1KCNH2TP53TSHR | |
| SCHEMBL14497096 | 0.86 | F10 (0.44) | F10KLKB1KCNH2TP53TSHR | |
| SCHEMBL14496458 | 0.86 | F10 (0.44) | F10KCNH2TP53TSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL5548478 | 0.85 | F10 (0.43) | F10KLKB1KCNH2TP53TSHR | |
| SCHEMBL14496431 | 0.84 | F10 (0.42) | F10KLKB1KCNH2TP53TSHR | |
| SCHEMBL14496435 | 0.84 | DEGS1 (0.48) | F10TP53TSHRNFKB1RAB9A | |
| SCHEMBL14496418 | 0.84 | GRM5 (0.48) | F10KCNH2TP53TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129371-A1 | Novel ethylenediamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129371-A1 | Novel ethylenediamine derivatives | C1R, C9, C1S | F10 238/4885KLKB1 2523/4885KCNH2 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.