Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 19/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.72 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5621096 | 0.93 | PTGER1 (0.75) | PTGER1CYP2C9MRGPRX4CYP3A4CYP2C19 | |
| SCHEMBL4151523 | 0.89 | PTGER1 (0.71) | PTGER1CYP2C9 | |
| SCHEMBL5619853 | 0.89 | PTGER1 (0.71) | PTGER1CYP2C9 | |
| SCHEMBL5620263 | 0.89 | PTGER1 (0.62) | PTGER1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL5620957 | 0.87 | PTGER1 (0.72) | PTGER1CYP2C9MRGPRX4 | |
| SCHEMBL4147844 | 0.86 | PTGER1 (0.66) | PTGER1CYP2C9 | |
| SCHEMBL5620756 | 0.85 | PTGER1 (0.81) | PTGER1CYP2C9MRGPRX4 | |
| SCHEMBL4154664 | 0.85 | PTGER1 (0.68) | PTGER1CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL5620283 | 0.85 | PTGER1 (0.74) | PTGER1CYP2C9 | |
| SCHEMBL4160335 | 0.85 | PTGER1 (0.72) | PTGER1CYP2C9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232821-B2 | (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives | GLAXO GROUP LIMITED (GB) | 2007-06-19 | — | — | US | disclosed |
| US-7232821-B2 | (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives | GLAXO GROUP LIMITED (GB) | 2007-06-19 | — | — | US | disclosed |